This publication from Science shares the rapid rise in SARS-CoV-2 cases in March of 2020 in New York City. Figure one above shows the number of patients with positive molecular tests for SARS-CoV-2 up to March 31 2020 compared to the daily number of patients with influenza A and influenza B tests in the 2019-2020 season.
AUTHORS: Ana S. Gonzalez-Reiche1,*,Matthew M. Hernandez2,3,*,Mitchell J. Sullivan1, Brianne Ciferri1, Hala Alshammary2, Ajay Obla1, Shelcie Fabre4, Giulio Kleiner2, Jose Polanco1,2, Zenab Khan1, Bremy Alburquerque1,3, Adriana van de Guchte1, Jayeeta Dutta1, Nancy Francoeur1, Betsaida Salom Melo1,5, Irina Oussenko1,5, Gintaras Deikus1,5, Juan Soto1,5, Emilia Mia Sordillo3,†,‡, Viviana Simon2,5,6,†,‡, Harm van Bakel1,8,†,‡
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Clinical Microbiology Laboratory, Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
The Mount Sinai Data Office, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Sema4, a Mount Sinai venture, Stamford, CT 06902, USA.
The Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
CORRESPONDING AUTHOR:
illo@mssm.edu (E.M.S.)
↵* These authors contributed equally to this work.
↵‡ These authors contributed equally to this work.
↵* These authors contributed equally to this work.
↵‡ These authors contributed equally to this work.
ABSTRACT: New York City (NYC) has emerged as one of the epicenters of the current SARS-CoV-2 pandemic. To identify the early transmission events underlying the rapid spread of the virus in the NYC metropolitan area, we sequenced the virus causing COVID-19 in patients seeking care at the Mount Sinai Health System. Phylogenetic analysis of 84 distinct SARS-CoV2 genomes indicates multiple, independent but isolated introductions mainly from Europe and other parts of the United States. Moreover, we find evidence for community transmission of SARS-CoV-2 as suggested by clusters of related viruses found in patients living in different neighborhoods of the city.
Science 29 May 2020:
eabc1917
DOI: 10.1126/science.abc1917
FIGURE 2:
